OpenAI Lets API Customers Pick a Processing Region Per Request

On August 21, 2026, OpenAI announced that API customers can select regional processing for an individual request by using a prefixed domain with an API key from a project having Global geography. Existing eligibility, data retention control, endpoint and model support requirements continue to apply.

OpenAI API data-residency compliance privacy

On August 21, 2026, OpenAI announced that API customers can now select regional processing for an individual request¹. The method is to use a prefixed domain together with an API key from a project having Global geography¹.

The company adds that existing eligibility, data retention control, endpoint and model support requirements continue to apply¹. What widened is the granularity of the call, not the conditions governing which regions are available. The changelog does not list the supported regions or the exact prefix, deferring to OpenAI’s data controls guide¹. For workloads carrying data residency requirements, the supported regions still need to be checked in that guide — much as with Mistral’s endpoints for keeping processing within Europe.